STEARINERIE DUBOIS, FRANCE

DERMAL

Spreading agents

DUBOIS offers a wide range of premium and excellent emollients helping you to spreadability and flexibility of your topical formulation with a minimal irritation risk

Chemical NameBrand NameEP/USP STATUS
DIISOPROPYL ADIPATEDUBCARE DIPAEP
ETHYL OLEATEDUBCARE OEEP/USP
DECYL OLEATEDUBCARE OD SEP
DIISOPROPYL SEBACATEBUD DIS-
PROPANEDIOL DICAPRYLATEDUB ZENOAT-
ISOPROPYL MYRISTATESTELLIESTERS IPMEP/USP
ISODECYL NEOPENTANOATEDUB VCI 10-
C12/C15 ALKYL BENZOATEDUBCARE B1215USP
ISONONYL ISONONANOATEDUB ININ-
ISODECYL ISONONANOATEDUB INID-
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATESTELLIESTERS 810 PGEP/USP
COCOYL CAPRYLOCAPRATEDUBCARE 810EP/USP
ISOPROPYL PALMITATESTELLIESTERS IPPEP/USP
CETEARYL ETHYLHEXANOATE & IPMSTELLIESTERS LIQUIDE-
CETEARYL ISONONANOATESTELLIESTERS In1618EP
METHYL PROPANEDIOLDUB DIOL-
BUTYL ADIPATEDUB BA-
PROPYLENE GLYCOL DIOCTOATEDUB DOPG-
CETYL PALMITATEDUBCARE PC 95EP
MYRISTYL MYRISTATEDUB MM 1315-
MYRISTYL LACTATEDUB LM S-

 

Thickening agents

DUBOIS dermatology range is composed of several esters with diverse consistency factors to optimize your formulas rheology.

Our excipients technical performance is the key for your formulation managers.

They can introduce smooth formulations with the desired viscosity and improving stability.

We also propose ingredients that modify the sensorial properties by reducing oiliness or tackiness and create a favorable skin feeling.

Chemical NameBrand NameEP/USP STATUS
PROPYLENE GLYCOL STEARATEDUBCARE SPGEP
GLYCERIDES HEMISYNTHETICDUB PP GRADEEP
DIETHYLENE GLYCOL STEARATEDUBCARE SDEGEP/USP
STEARIC ACID 50/50DUBCARE STEAEP/USP
MONOETHYLENE GLYCOL STEARATEDUBCARE SMEGEP/USP
GLYCERYL STEARATE Type 1DUBCARE G50EP
GLYCERYL STEARATE Type 2DUBCARE GMSEP/USP
GLYCERYL STEARATE Type 2DUBCARE GMS PLUSEP/JP
STEARIC ACID 95%DUBCARE STEA 95EP
GLYCERYL DIBEHENATESTELLIESTERS DBHGEP/USP
CARNAUBA WAXEZ-COAT CWMEP/USP

Emulsifying & co-emulsifying agents

DUBOIS pharmaceutical solubilizers and emulsifiers provide good solutions taking into consideration your API’s nature.

Our emulsifiers will also improve bioavailability and permeability of your hydrophobic API’s.

Chemical NameBrand NameEP/USP STATUS
PROPYLENE GLYCOL STEARATEDUBCARE SPGEP
MONOETHYLENE GLYCOL STEARATE DUBCARE SMEGEP/USP
GLYCERYL STEARATE Type 1DUBCARE G50EP
GLYCERYL STEARATE Type 2DUBCARE GMSEP/USP*
GLYCERYL STEARATE Type 2DUBCARE GMS PLUSEP/JP
DIETHYLENE GLYCOL STEARATEDUBCARE SDEGEP/USP
CETEARYL ALCOHOL & CetearethDUB SC 20Used into AMM product
SUCROESTERSSTELLIESTERS SE 5SEP/USP
PEG-6 STEARATE & PEG-32 STEARATE & GLYCOL STEARATEDUB 1632Used into AMM product
GLYCERYL STEARATE & PEG-100 STEARATEDUB 165
PEG-6 STEARATE & PEG-32 STEARATEDUB 315
GLYCERYL STEARATE & PEG-75 STEARATE & CETYLDUB 340
ALCOHOL & STEARETH-20 & CETEARETH 20
SUCROESTERSSTELLIESTERS SE 15EP/USP
GYLCERYL OLEATEDUBCARE OGEP/USP
OLEOYL POLYOXYLGLYCERIDESDUBCARE OLGA SFEP/USP
LINOLEOYL POLYOXYLGLYCERIDESDUBCARE GPE MEP/USP
CAPRYLOCAPRYOL POLYOXYLGLYCERIDESDUBCARE GPE 810EP/USP

Oral Route

Lubricants

Lubrication is a critical step to ensure the success os the pharmaceutical solid forms. Dubois proposes hydrophobic lubricants to

face friction, capping and solid form behaviors.

Chemical NameBrand NameEP/USP STATUS
SUCROESTERS STELIIESTERS SE 15PEP/USP
STELIIESTERS SE 15SEP/USP
STELIIESTERS SE 5SEP/USP
COMPOUNDDUB HYDROLUBEP Blend
DUB HYDROLUB FFOOD
MAGNESIUM STEARATEDUB SMG PHARMAEP/USP
STEARIC ACIDSTELLIPRESS 1200 POUDREEP/USP
STELLIPRESS MICROEP/USP
STELLIPRESS 30/70 MICROEP/USP/JP
STELLIPRESS MICRO 95EP
STELLIESTERS DBHGEP/USP
STELLIESTERS DBSEP/USP

Binders, Control release agents & Matrix

How to overcome the challenge involved when developing controlled release formulations?

A smart choice of the duo binder/control release agent is the success key to protect, target and perfectly deliver your API

Chemical NameBrand NameEP/USP STATUS
CETYL PALMITATEDUBCARE PC 95EP/USP
STEARIC ACIDDUBCARE STEAEP/USP
GLYCERYL STEARATEDUBCARE G50 type 1
DUBCARE GMS type 2
DUBCARE GMS PLUS type 2
EP
EP/USP
EP/JP
SEMI-SYNTHETIC GLYCERIDESDUB PP RANGEEP
STEARIC ACIDDUBCARE STEA 95EP
GLYCERYL DIBEHENATESTELLIESTERS DBHG PELLETEP/USP
CARNAUBA WAXEZ-COAT CWMEP/USP

Oral Bioavailability enhancers, Solubilizers & Co-emulsifying agents

Today, there are more and more hydrophobic active molecules in the pipelines. Enhancing bioavailability by improving the solubility

is the main challenge for R&D laboratories to reach market.

Chemical NameBrand Name 
OLEOYL POLYOXYLGLYCERIDESDUBCARE Olga SFEP/USP
LINOLEOYL POLYOXYLGLYCERIDESDUBCARE GPE MEP/USP
SUCROESTERSDUB SE 3SFOOD
SUCROESTERSSTELLIESTERS SE 5S EP
MEDIUM CHAIN TRIGLYCERIDESSTELLIESTERS MCTEP/USP
ETHYL OLEATEDUBCARE OEEP/USP
GLYCERYL LINOLEATEDUB LIGEP
CAPRYLOCAPRYOLPOLYOXYLGLYCERIDESDUBCARE GPE 810EP/USP
SUCROESTERSSTELLIESTERS SE 15SEP/USP
SUCROESTERSSTELLIESTERS SE 15PEP/USP
PEG 300 STEARATEDUBCARE SPEG 6EP/USP
PEG 300 STEARATEDUBCARE SPEG 8EP/USP

Rectal & vaginal route

Coconut origin

Range Product Melting point* (C°) Hydroxyl Value** Referance
LOW MELTING POINT PP KB 1 32-33,5 May-15 Ph.Eur.,USP/NF
PP KBC 5 32,5-34,5 40-50 Ph.Eur.,USP/NF
MEDIUM MELTING POINT PP KCD 0 33,5-35,5 max 3 Ph.Eur.,USP/NF
PP KCD 1 33,5-35,5 May-15 Ph.Eur.,USP/NF
PP KCD 3 33,5-35,5 20-30 Ph.Eur.,USP/NF
PP KCD 5 33,5-35,5 40-50 Ph.Eur.,USP/NF
PP KD 3 34-36 20-30 Ph.Eur.,USP/NF
PP KCD 4 33,5-35,5 30-40 Ph.Eur.,USP/NF
HIGH MELTING POINT PP KE 3 35,5-37,5 20-30 Ph.Eur.,USP/NF
PP KF 1 36-38 May-15 Ph.Eur.,USP/NF
PP KG 1 37-39 max 15 Ph.Eur.,USP/NF
SPECIALITY BASES PP KB 5*** 32-34 30-60 Saturated polyglycolized glycerides
PP AT 5*** 31-35 50-70 Ph.Eur.,USP/NF With additive
PP AX 5*** 32-35 50-70 Ph.Eur.,USP/NF With additive
PP KABR 6*** 31,5-33 60-70 Ph.Eur.,USP/NF With additive

Melting point : Ph. Eur. 2.2.15

Hydroxyl Value: Ph. Eur. 2.5.3

These grades are mixtures of Hard Fats (EP) and additives, These mixtures do not comply with EP

Rectal & vaginal route

Palm/Palm kernel origin

Range Product Melting point* (C°) Hydroxyl Value** Referance
LOW MELTING POINT PP B 1
PP C3
PP CD 1
PP DY 0
PP D 1
PP D 3
32-35
33-35
33,5-33,5
34-63
34-36
34-36
0-10
20-30
0-10
max 2
0-10
20-30
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
MEDIUM MELTING POINT PP E 1
PP E 3
PP EF 3
PP F 1
35-36,5
35-36,5
35,5-37,5
36-37,5
0-10
20-30
20-30
0-10
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
HIGH MELTING POINT PP G 1
PP G 3
PP H 1
PP M 1
37-39
37-39
38-40
42-44
0-10
20-30
0-10
0-10
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
Ph.Eur.,USP/NF
SPECIALITY BASES PP CDL 1***
PP DL 1***
PP E 5***
33,5-35,5
34-36
34-37
0-15
0-10
30-50
Ph.Eur.,USP/NF With additive
Ph.Eur.,USP/NF With additive
Saturated polyglycolized glycerides

Melting point : Ph. Eur. 2.2.15

Hydroxyl Value: Ph. Eur. 2.5.3

These grades are mixtures of Hard Fats (EP) and additives, These mixtures do not comply with EP