SHINETSU CHEMICAL CO., JAPAN

HYPROMELLOSE (METOLOSE® )

Grade

Labeled Viscosity

(mPa?s)*

Substitution Type

Regulatory Status

Applications

METOLOSE® 60SH-50

50

2910

USP/EP/JP; DMF, CDMF available

·    Suspending agent

·    Preferred for ophthalmic use

·    Forms clear films

·    SR matrix forming agent

METOLOSE® 60SH-4000

4000

METOLOSE® 60SH-10000

10000

METOLOSE® 65SH-50

50

2906

USP/EP/JP; DMF, CDMF available

·    Suspending agent

·    Binder for wet granulation

METOLOSE® 65SH-400

400

METOLOSE® 65SH-4000

4000

METOLOSE® 90SH-4000

4000

2208

USP/EP/JP; DMF, CDMF available

·    Dermal patches

·    Thickening agent

·    Suspending agent

·    SR matrix forming agent

METOLOSE® 90SH-15000

15000

METOLOSE® 90SH-100000

100000

* 2 wt% aqueous solution at 20°C according to the USP measuring method

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